Side Effects. Problems associated with diarrhea are fluid and potassium loss in the diarrheal stool leading to dehydration. Colace side effects. 9% NaCl. Lactulose (Kristalose) is a synthetic, non-digestible double-sugar (disaccharide) used to treat chronic constipation and a complication of liver disease. 3 g galactose and lactose as a total sum. KRISTALOSE (lactulose) is a synthetic disaccharide in the form of crystals for reconstitution prior to use for oral administration Each. nausea or vomiting. Adult: The usual adult, oral dosage is 2 to 3 tablespoonfuls (30 to 45 mL, containing 20 g to 30 g of lactulose) three or four times daily. Twenty-four to 48 hours may be required to produce a normal bowel movement. GoodRx has partnered with InsideRx and Cumberland Pharmaceuticals to reduce the price for this prescription. Administer with a full glass (240 mL) of water or juice. Call your doctor for medical advice about side effects. The information contained herein is not intended to cover all possible side effects, precautions, warnings, drug interactions, allergic reactions, or adverse effects. corresponding to 10-30 g lactulose. Lactulose, Constulose. Lactulose. Kristalose Side Effects. Lactulose has an average rating of 7. 0 to 7. [3] [4] It is administered orally for constipation, and either orally or rectally for hepatic encephalopathy. The drug dissolves quickly in four ounces of water, offering. Administer with a full glass (240 mL) of water or juice. The NADAC wholesale price of Kristalose 66220-719-30 has fluctuated from a low of $2. Lactulose (Cephulac,Constulose, Duphalac, Enulose, Kristalose). Cascara Sagrada Aromatic Fluid Extract. What is Kristalose used for? Kristalose is used to treat constipation. Trademarks, brands, logos, and copyrights are the property of their respective owners. KRISTALOSE (lactulose) is a synthetic disaccharide in the form of crystals for reconstitution prior to use for oral administration Each 10 g of lactulose contains less than 0. Add to Cart. Then, squeeze the enema to insert the fluid into the rectum. Therapeutic effect may occur after 2-3 days of treatment. Hourly doses of 30 to 45 mL of lactulose solution may be used to induce the rapid. Dewasa. It also increases pressure, which prompts the muscles in your intestines to move stool. Diarrhea. This softens the stool, making it easier to have a bowel movement. 3 g of galactose and lactose total) Bertek, (also promoted by Cumberland) 20 g/packet. Dissolve single dose packets (Kristalose) in 4 oz of water. Side Effects. Lactulose is a colonic acidifier that works by increasing stool water content and softening the stool. If you have any questions, ask your doctor or pharmacist. Nine percent (9%) of patients were discontinued from BENTYL because of one or more of these side effects (compared with 2% in the placebo group). Lactulose is a colonic acidifier which promotes laxation. 1. Ammonium Detoxicant; Hyperammonemia Agent; Laxative, Miscellaneous. You should consult your health care professional before taking any drug, changing your diet, or commencing or discontinuing any course of treatment. Lactulose is also used to reduce the amount of ammonia in the blood of patients with liver disease. 5% in those aged over 60 years [], with a higher susceptibility in females and individuals under a low socioeconomic status [1, 2]. Diarrhea (loose stool) may occur if the dose of lactulose is too high. En pacientes con antecedentes de estreñimiento crónico, el tratamiento con lactulosa aumenta la cantidad de defecaciones por día y la cantidad de días en los que se producen tales defecaciones. Lactulose is a non-absorbable sugar used in the treatment of constipation and hepatic encephalopathy. Medscape - Constipation dosing in Enulose, Kristalose (lactulose), frequency-based adverse effects, comprehensive interactions, direction, pregnancy & lactation schedules, and cost information. 30 mins to 96 hours- oral 15-30 mins- rectal. unusual tiredness or weakness. Important: How to use this information. Lactulose is a prescription medication that eases constipation in cats and dogs and can also be beneficial in treating liver disease. Brand names for lactulose include Constulose, Enulose, and Kristalose. Lactulose is used to treat constipation. Medscape - Congestion dose for Enulose, Kristalose (lactulose), frequency-based adverse effects, comprehensive interactions, contraindications, fertility & lactation dates, and cost information. A unique, dry powder crystalline formulation of lactulose, Kristalose is designed to enhance patient compliance in the treatment of acute and. Constipation is a very common problem for all ages. We use cookies to improve security, personalize the user experience, enhance our marketing activities (including cooperating with our marketing. GoodRx has partnered with InsideRx and Sebela Pharmaceuticals to reduce the price for this prescription. STORE AT ROOM TEMPERATURE, 15°. Solution should be colorless to slightly pale yellow. Common side effects of MiraLAX include: nausea, abdominal cramping, bloating, upset stomach, gas, dizziness, or. , during the weekend, or on a holiday, call 212-639-2000. It is the same product, but comes in a different concentration than Enulose ®, which is the most common brand used in veterinary medicine. Xifaxan has an average rating of 6. So what does Kristalose do?乳果糖. Newer antihistamines — like loratadine (Claritin) and fexofenadine (Allegra) — are also less likely to cause constipation. Dry mouth, increased thirst, muscle cramps, severe nausea or vomiting. Osmotic laxatives, like Miralax, can take a bit longer to work but typically have fewer side effects. Stomach pain or cramps. Stress can cause changes in the release and action of the neurotransmitters in the bowel. It may help to increase the number of bowel movements per day and the number of days you have a bowel movement. In other words, oxycodone can prevent your digestive tract from working as it should — resulting in constipation. There are currently no generic alternatives for Kristalose. Less serious side effects may include: gas, mild nausea or stomach cramps; or. It is a man-made sugar solution. Drink fluids and stay well hydrated when using laxatives. Find medical information for Kristalose on epocrates online, including its dosing, contraindications, drug interactions, and pill pictures. It may be used by mouth or rectally. 3 g galactose and lactose as a total sum. The drug is only available from compounding pharmacies in most countries. Lactulose (Kristalose) is a synthetic, non-digestible double-sugar (disaccharide) used to treat chronic constipation and a complication of liver disease. The pH range is 3. com. It is a non-absorbable disaccharide which draws water into the bowel. It helps increase the number of bowel movements per day and the number of days on which bowel movements occur in patients with a history of chronic (long-lasting) constipation. nausea or vomiting. In one small. Each powder packet contains 10 grams or 20 grams of lactulose. Kristalose 10000 MG Powder for Oral Solution is sometimes used to treat or prevent certain conditions of the brain that are caused by liver failure, which can lead to confusion, problems with memory or thinking, behavior changes, tremors, feeling irritable. Lactulose should only be given during pregnancy when need has been clearly established. com. Dalam kondisi akut, laktulosa dapat diberikan setiap 1–2 jam. Treatment. UNSPSC Code. It may help to increase the number of bowel movements per day and the number of days you hav. Lactulose has an average rating of 7. En pacientes con antecedentes de estreñimiento crónico, el tratamiento con lactulosa aumenta la cantidad de defecaciones por día y la cantidad de días en los que se producen tales defecaciones. Este medicamento también puede ser prescrito para otros usos; pídale más información a su doctor o. Much larger or overweight cats close to 20lb may need higher doses of 1-2ml. 2 million for Sancuso. It is categorized in a drug class called guanylate cyclase-C agonists. Lactulose. Kristalose ( lactulose) powder is a laxative derived from lactose. LACTULOSE (LAK tyoo lose) treats constipation. Lactulose has an average rating of 7. marvistavet. Your doctor may recommend these if your constipation is severe and other treatments haven’t worked. 5 mL of the liquid. a sudden change in bowel habits lasting longer than 2 weeks. KRISTALOSE (lactulose) is a synthetic disaccharide in the form of crystals for reconstitution prior to use for oral administration Each 10 g of lactulose contains less than 0. Common side effects of GoLYTELY may include: vomiting, stomach pain, indigestion, bloating; rectal pain or irritation; hunger, thirst, mild nausea; trouble sleeping; or. severe diarrhea. Plumb's Veterinary Drug Handbook says that "one gram of the crystals is equivalent to 1. Find everything you need to know about Kristalose, including what it is used for, warnings, reviews, side effects, and interactions. 81% of reviewers reported a positive effect, while 13% reported a negative effect. muscle pain, cramps, or twitching. Osmotic laxative. ". 67% of reviewers reported a positive effect, while 22% reported a negative effect. 3 g galactose and lactose as a total sum. nausea or vomiting. ST. 34679 to a high of $8. For assistance with the Kristalose® Web Coupon, contact 1-855-584-6194. Gas, bloating, burping, stomach rumbling/pain, nausea, and cramps may occur. If you are using the crystals in packets, dissolve the contents of the packet in half a glass of water (4. com. 1 out of 10 from a total of 253 ratings on Drugs. Common MiraLAX side effects may include: bloating, gas, upset stomach; dizziness; or. Save or instantly send your ready documents. Lactulose is a colonic acidifier that works by increasing stool water content and softening the stool. 80. The pH range is 3. Email to a Friend. Lactulose, Constulose. If any of these effects last or get worse, tell your doctor or pharmacist promptly. It works by increasing the amount of water your intestine absorbs. The dose of lactulose solution is 0. Label: KRISTALOSE- lactulose powder, for solution Label RSS; ShareMedicare prices are provided by the Centers for Medicare and Medicaid Services (CMS). Trademarks, brands, logos, and copyrights are the property of their respective owners. Generic Equivalent To Cephulac, Chronulac, Constilac, Constulose, Duphalac, Evalose. It is a man-made sugar solution. 67% of reviewers reported a positive effect, while 22% reported a negative effect. Drug Monograph. Kristalose ®. The pH range is 3. Exercise most days of the week. This softens the stool, making it easier to have a bowel movement. Lactulose has an average rating of 7. Adding more water and fiber to the diet are often the first options to relieve constipation symptoms. KRISTALOSE™ (LACTULOSE) is a synthetic disaccharide in the form of crystals for reconstitution prior to use for oral administration. This product is available in the following dosage. 2 g lactose, and 1. 1 out of 10 from a total of 253 ratings on Drugs. These moisten and lubricate the stool making it easier to pass. Lactulose is FDA-approved for human use under the brand names Constulose ®, Enulose ®, Generlac ®, and Kristalose ®. It may help to increase the number of bowel movements per day and the number of days you have a bowel movement. Lactulose is a member of the laxatives drug class and is commonly used for Constipation - Acute, Constipation - Chronic, and Hepatic Encephalopathy. Pay the initial $5, and you could receive up to $200 off your 30 day supply of Kristalose®. This softens the stool, making it easier to have a bowel movement. Mix 300 mL of lactulose with 700 mL of water or 0. These include bulk-forming laxatives like Fibercon, stool softeners, and osmotic laxatives like Miralax. Osmotic laxatives (such as lactulose. It is a symptom rather than a disease and, despite its frequency, often remains unrecognized until the patient develops sequelae, such as anorectal disorders or diverticular disease. Linaclotide (Linzess®). comAnswers. Lactulose is a disaccharide derivative of lactose used to treat constipation and portal systemic encephalopathy. Compare prices and print coupons for Constulose (Lactulose) and other drugs at CVS, Walgreens, and other pharmacies. The chemical name for lactulose is 4-O-β-D. Mammals and birds are not able to digest lactulose, so it passes unabsorbed from the mouth all the way down to the large intestine. Kristalose 10 GM Granules for Oral Solution is sometimes used to treat or prevent certain conditions of the brain that are caused by liver failure, which can lead to confusion, problems with memory or thinking, behavior changes, tremors, feeling irritable, sleep. 57% of reviewers reported a positive effect, while 35% reported a negative effect. The dosage can vary depending on which type you take. It also increases pressure, which prompts the muscles in your intestines to move stool. KRISTALOSE® (LACTULOSE) is a synthetic disaccharide in the form of crystals for reconstitution prior to use for oral administration. KRISTALOSE (lactulose) is a synthetic disaccharide in the form of crystals for reconstitution prior to use for oral administration Each 10 g of lactulose contains less than 0. Diarrhea . viral gastroenteritis. This is not a complete list of side effects and others may occur. Do not take 2 doses at the same time or extra doses. 3 g galactose and lactose as a total sum. Learn about dosage, side effects, uses, and more. If you're a patient at MSK and you need to reach a provider after 5 p. com. Kristalose is covered by some Medicare and insurance plans. 0 to 7. Constipation is blamed for many complaints (abdominal pain, nausea, fatigue, anorexia) that are actually symptoms of an underlying problem (eg, irritable bowel syndrome [IBS], depression). If you encounter any issues, please let us know . Filter by condition. Lactulose is a sugar solution, a disaccharide, created from two separate sugars. It has also been used in the treatment of liver disease to help prevent ammonia from building up in the blood. seizures. 3 out of 10 from a total of 3 ratings on Drugs. Kristalose 20gm packet How to Take Kristalose Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup. Check the medication label if you have diabetes, high blood pressure, phenylketonuria (PKU), or if you are on a low-salt diet. Solution should be colorless to slightly pale yellow. 4 out of 10 from a total of 143 ratings on Drugs. This drug is less popular than comparable drugs. KRISTALOSE (lactulose) is a synthetic disaccharide in the form of crystals for reconstitution prior to use for oral administration Each 10 g of lactulose contains less than 0. Lactulose is a colonic acidifier which promotes laxation. Lactulose Pregnancy Warnings. One of the most commonly used drugs is lactulose (trade name Kristalose). Kristalose active ingredients, usages, indications, composition, dosages and other pharmaceutical product information. rectal irritation. Lactulose is a. [3] It generally begins working after 8–12 hours, but may take up to 2 days to improve constipation. Find patient medical information required Lactulose (for Encephalopathy) oral on WebMD including its usage, side gear and safety, human, pictures, warnings both users ratings. 67% of reviewers reported a positive effect, while 22% reported a negative effect. Lactulose is metabolized in the colon by colonic bacteria to. Severe stomach pain, bloating, vomiting, or diarrhea. Complete KRISTALOSE For Oral Solution Sample Request Form - Rxassist 2020-2023 online with US Legal Forms. swelling of the feet or lower legs. And they work well for constipation caused by medications. Laxatives are generally classified according to their mode of action: bulk‐forming laxatives, osmotic laxatives, stimulant laxatives, and faecal softeners and lubricants. Delivery & Return Free Shipping. 7 g/day (2. Save $164. The dose may be increased to 60 mL daily if necessary. Lactulose is also available as crystal meant to be mixed in liquids for human use (Kristalose). Linaclotide (Linzess) and. The NDC code 66220-729 is assigned by the FDA to the product Kristalose which is a human prescription drug product labeled by Cumberland Pharmaceuticals Inc. DrugBank Accession Number. lactulose. Do not use this. In addition to adjusting your diet and lifestyle habits, you may need to use laxatives. Prices Medicare Drug Info Side Effects. MiraLAX is a brand-name, over-the-counter product that’s typically used to treat short-term constipation. Lactulose is the standard of care till this date; however, polyethylene glycol (PEG) has gained the attention of multiple investigators. 5 million physician visits and 92,000 hospitalizations each year. Kristalose (Oral) Generic name: lactulose [ LAK-tue-lose ] Drug class: Laxatives. They add volume to your stool to help push it through your. Kristalose (Generic) lactulose. Kristalose powder is a laxative derived from lactose. This drug is less popular than comparable drugs. Hyperosmolar laxatives are indigestible, unabsorbable compounds that remain within the colon and retain the water that already is in the colon. It may help to increase the number of bowel movements per day and the number of days you have a bowel movement. 30-45mg PO TID or QID or (300mL in 700cc H2O retention enema x30min) titrate for 2-3 soft stools per day; Constipation. 3 g galactose and lactose as a total sum. 10, FD & C Yellow No. Zelnorm and Amitiza are both used to treat IBS-C in adult women. These conditions can lead to. 6 g galactose, less than 1. It belongs to a group of medications called laxatives. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. It may help to increase the number of bowel movements per day and the number of days you have a bowel movement. The 3-hour SIBO profile. (February 26, 2008) – Kristalose®, a prescription laxative product that treats acute and chronic constipation,. Frequency can vary from every 6-8 hours depending on the. Fruits, vegetables, and whole grains are a great natural source of fiber. Last updated on Sep 7, 2023. Stool softeners can be used to help decrease bowel movement straining caused by constipation. Generic name: lactulose. Medicaid. One of the most commonly used drugs is lactulose (trade name Kristalose). Maintenance dose: 15-30 mL (10-20 g or 1-2 sachets) daily. Stimulant laxatives cause the intestine to contract, moving the stool. Symptom treatment should be based on etiology when possible. Qty. nausea or vomiting. USES: This medication is a laxative used to treat constipation. Popular Searches. The sugar Lactulose has a laxative effect that eases constipation and gastric distress in both dogs and cats. Lactulose Prices, Coupons and Patient Assistance Programs. The medication comes as a powder that’s dissolved in water. Gas, bloating, burping, stomach rumbling/pain, nausea, and cramps may occur. Kristalose Rx: Summary Description and Clinical Pharmacology Indications and Dosage Warnings and Precautions Side Effects and Adverse Reactions Drug Interactions, Overdosage, Contraindications, Other Rx Info Active Ingredients : News & Research: News in Media Published Studies Curr't Clinical Trials :Kristalose 167 MG/ML Oral Solution is used to treat chronic constipation. 67% of reviewers reported a positive effect, while 22% reported a negative effect. This is not a complete list of side effects and others may occur. diarrhea, abdominal pain, gas, bloating, headache, and. 5 mL/kg, PO, BID–TID. Side effects include gas, diarrhea, upset. MAIL-IN REBATE10 Gram. Kristalose-20-GM-Powder-for-Oral-Solution. Constipation is a very common problem for all ages. Talk with your doctor. 0 to 7. Lactulose is currently not FDA approved as a veterinary medication. This information from Lexicomp® explains what you need to know about this medication, including what it’s used for, how to take it, its side effects, and when to call your healthcare provider. Prices start at $10. Use on your skin only. , _____ is when idiopathic constipation occurs frequently and is associated with chronic or recurrent abdominal discomfort that is relieved by defecation. It is a unique, proprietary, crystalline form of lactulose, with no restrictions on length of therapy or patient age. Medically reviewed by Drugs. 0. More studies are being done that point to Xifaxan having a greater impact on improved. Stimulants. com. Lactulose is a disaccharide derivative of lactose used to treat constipation and portal systemic encephalopathy. Doctors also prescribe it for a brain disorder caused by liver disease. Treatment. Check our savings tips for co-pay cards, assistance programs, and other ways to reduce your cost. This medication is a laxative used to treat constipation. Lactulose (Oral Route) Merative, Micromedex. Lactulose is available as a solution and a powder in packets. KRISTALOSE ® (lactulosa) para solución oral está indicado para el tratamiento del estreñimiento. Dehydration and electrolyte problems can happen in people who have diarrhea. Seek medical care or call 911 at once if you have the following serious side effects: Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision ,eye painor swelling, or seeing halos around lights;Lactulose is a disaccharide: a sugar molecule composed of two smaller sugar molecules bonded together, in this case, fructose and galactose. COMMON BRAND NAME (S): Cephulac, Chronulac, Constilac, Constulose, Duphalac, Evalose. Drug Summary What Is Kristalose? Kristalose (lactulose) For Oral Solution is a synthetic disaccharide indicated for the treatment of constipation. Learn more about Medicare prescription drug plans and savings with GoodRx. In addition to adjusting your diet and lifestyle habits, you may need to use laxatives. Other common OTC products in this group include Citrucel, Metamucil, and Colace. Prunes and bran cereal are tried and true constipation remedies. The most common names for osmotic and hypertonic laxatives include Fleet Phospho-Soda, lucatose (Kristalose), magnesium hydroxide (Milk of Magnesia or MOM), lactitol (Pizensy), and polyethylene glycol (Miralax). What the brain perceives as stress is also perceived as stress by the bowels. Generlac has an average rating of 10. Therapeutic effect may occur after 2-3 days of treatment. 92Osmotic laxatives, when taken orally, can cause these side effects: Burning sensation. Doctors also prescribe it for a brain. The dose for lactulose for hepatic encephalopathy is 1-3 milliliters per 10 kilograms (not per a single kilogram). En pacientes con antecedentes de estreñimiento crónico, el tratamiento con lactulosa aumenta la cantidad de defecaciones por día y la cantidad de días en los que se producen tales defecaciones. You may experience gas and bloating when first starting treatment with. 3 g galactose and lactose as a total sum. increased sweating. m. Search the SingleCare website for prescription coupons—our customers regularly save up to 80% on prescription prices, and what’s more, the coupons can be applied to refills as well. Descriptions. KRISTALOSE (Brand for LACTULOSE) Monographs Lactulose, a synthetic derivative of lactose, is a disaccharide sugar containing one molecule of galactose and one molecule of fructose. Lactulose works by. Constipation isn’t guaranteed to happen to everyone taking opioids like oxycodone, but it’s very common. Much larger or overweight cats close to 20lb may need higher doses of 1-2ml. Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing. As a result, oral doses of lactulose reach the colon virtually unchanged. Uses;. Kristalose dissolves quickly in 4 oz. Eat prunes and bran cereal. Learn about Enulose What it is used for, how to take Enulose, serious side effects, food and drug interactions, forms, doses, safe storage, and FAQs. 57% of reviewers reported a positive effect, while 35% reported a negative effect. Kristalose Prices, Coupons and Patient Assistance Programs. Mix the syrup, liquid or drops in 4 to 8 ounces of fruit juice, milk or infant formula to prevent throat irritation and mask a bitter taste. It is used to treat or prevent certain brain or mental problems caused by liver disease. In patients with a history of chronic constipation, lactulose therapy increases the number of bowel movements per day. The packets are supplied as follows: NDC 66220-719-30 (Carton of thirty 10 g packets) NDC 66220-729-30 (Carton of thirty 20 g packets). increased sweating. Remember that this. There is a $3,400 maximum. It is broken down in the large intestine into mild acids that draw water into the colon, which helps soften the stools. This was irrespective of routes of administration (oral, rectal or another route) and for doses that were evaluated in the management of constipation in palliative care. Distention (bloating) of abdomen, cramping, a feeling of pressure in the lower abdomen. Follow all instructions closely. GoodRx is not sponsored by or affiliated with any of the third-party brands identified. 當治疗便秘時須以口服給藥，治疗肝性脑病时則可以口服或直肠给药 [3] 。. KRISTALOSE® (Lactulose) For Oral Solution is available in single dose packets of 10 g (NDC 66220-719-01) and single dose packets of 20 g (NDC 66220-729-01). This softens the stool, making it easier to have a bowel movement. However, because bacterial overgrowth can mimic other malabsorptive disorders (eg, Crohn disease Crohn Disease Crohn disease is a chronic transmural inflammatory bowel disease that usually affects the distal ileum and colon but may occur in any part of the. Powdered Kristalose is not as heavy or bulky to store as Lactulose Solution. Medication Summary. It may. Dry mouth, increased thirst, muscle cramps, severe nausea or vomiting. Remember that this. Diarrhea. Tier 1 products are available with no authorization necessary. Drinking more water can also help with constipation from medication. Label: KRISTALOSE- lactulose powder, for solution Label RSS; Share muscle pain, cramps, or twitching. 30-45 ml (20-30 g) orally every 6-8 hours, adjusted until 2-3 soft stools/day; if acute, may be given every 1-2 hours until 2-3 soft stools/day. Constipation is common in postmenopausal women. The product's dosage form is powder, for solution and is administered via oral form. electrolyte imbalance gas dehydration. rectal bleeding; black, bloody, or tarry stools; weakness, dizziness; or. . See a doctor if you are still constipated after five days of taking sodium picosulfate. KRISTALOSE ® (LACTULOSE) is a synthetic disaccharide in the form of crystals for reconstitution prior to use for oral administration. This medication is a laxative used to treat constipation. Fiber supplements can effectively induce bowel movements if a low fiber diet is the cause of your constipation. Generlac; Kristalose. The pH range is 3. Type. Lactulose is also available as crystal meant to be mixed in liquids for human use (Kristalose). Lactulose Which relieves chronic constipation more effectively? Chronic constipation is a disorder in which an individualKristalose Side Effects Gas, bloating, burping, stomach rumbling/pain, nausea, and cramps may occur. Kristalose Used for Constipation expand_more Pay as little as $5 for Kristalose Pay the initial $5, and you could receive up to $200 off your 30 day supply of Kristalose®. Lactulose is used to treat chronic constipation. 3 g galactose and lactose as a total sum. Whole grains, such as brown rice and oats. Use Kristalose medicine regularly to get the most benefit from it. The Kristalose would cause my CIC colon to produce 2 bowel movements a week instead of the usual 1 a week. 64% of reviewers reported a positive effect, while 24% reported a negative effect. or as directed by your doctor. Easily fill out PDF blank, edit, and sign them. 2. It helps to treat chronic constipation. Confusion, weakness, and muscle twitching.